HitPredict

Interactor 1: HSP82 (P02829)
ATP-dependent molecular chaperone HSP82 (82 kDa heat shock protein) (Heat shock protein Hsp90 heat-inducible isoform)
Gene: HSP82

Interactor 2: ACT (P60010)
Actin (EC 3.6.4.-)
Gene: ACT1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.693

Property	Details
Experiments	26217697, 15879519, 25452130, 31399574
Identification Methods	affinity chromatography technology, two hybrid, two hybrid array
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 709 Sc			1 375
+	Hs
		438064 HS90B_HUMAN (5-709): 0: 1026: 62.13		ACTG_HUMAN (1-375): 0: 600: 89.07
+	Hs
		431726 HS90A_HUMAN (4-709): 0: 1015: 60.83		ACTG_HUMAN (1-375): 0: 600: 89.07
+	Sc
		544238 HSC82_YEAST (1-709): 0: 973: 94.64		ACT_YEAST (1-375): 0: 594: 100.00
+	Hs
		538189 ENPL_HUMAN (3-684): 0: 904: 45.97		ACTC_HUMAN (2-375): 0: 591: 87.17