HitPredict

Interactor 1: HSP82 (P02829)
ATP-dependent molecular chaperone HSP82 (82 kDa heat shock protein) (Heat shock protein Hsp90 heat-inducible isoform)
Gene: HSP82

Interactor 2: UBP3 (Q01477)
Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.4.19.12) (Deubiquitinating enzyme 3) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3)
Gene: UBP3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	26804907, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 709 Sc			1 912
+	Sc
		544257 HSC82_YEAST (1-709): 0: 973: 94.64		UBP3_YEAST (1-912): 0: 747: 100.00
+	Hs
		431988 HS90A_HUMAN (4-709): 0: 1015: 60.83		UBP49_HUMAN (245-912): 1.6e-86: 293: 14.71
+	Sc
		543786 HSC82_YEAST (1-709): 0: 973: 94.64		UBP5_YEAST (288-910): 2.18e-79: 276: 16.72
+	Sc
		366696 HSP82_YEAST (1-709): 0: 984: 100.00		UBP10_YEAST (135-910): 3.35e-75: 264: 13.89
+	Sc
		544191 HSC82_YEAST (1-709): 0: 973: 94.64		UBP10_YEAST (135-910): 3.35e-75: 264: 13.89
+	Sc
		366180 HSP82_YEAST (1-709): 0: 984: 100.00		UBP13_YEAST (355-909): 4.68e-70: 249: 15.45
+	Sc
		366580 HSP82_YEAST (1-709): 0: 984: 100.00		UBP8_YEAST (589-911): 5.51e-73: 249: 19.82
+	Sc
		543617 HSC82_YEAST (1-709): 0: 973: 94.64		UBP13_YEAST (355-909): 4.68e-70: 249: 15.45
+	Sc
		544074 HSC82_YEAST (1-709): 0: 973: 94.64		UBP8_YEAST (589-911): 5.51e-73: 249: 19.82