HitPredict

Interactor 1: HSP82 (P02829)
ATP-dependent molecular chaperone HSP82 (82 kDa heat shock protein) (Heat shock protein Hsp90 heat-inducible isoform)
Gene: HSP82

Interactor 2: PRS8 (Q01939)
26S proteasome regulatory subunit 8 homolog (Protein CIM3) (Protein SUG1) (Tat-binding protein TBY1)
Gene: RPT6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31399574, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0016887 - ATP hydrolysis activity
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 709 Sc			1 405
+	At
		137806 HS904_ARATH (3-709): 0: 994: 61.72		PRS4A_ARATH (11-395): 5.61e-138: 403: 44.16
+	Sc
		544264 HSC82_YEAST (1-709): 0: 973: 94.64		PRS8_YEAST (1-405): 6.47e-132: 386: 100.00
+	Ca
		804520 HSP90_CANAL (4-709): 0: 959: 81.75		Q5A6S2_CANAL (2-404): 1.31e-118: 353: 39.95
+	Sc
		366381 HSP82_YEAST (1-709): 0: 984: 100.00		PRS4_YEAST (72-395): 3.99e-106: 321: 49.85
+	Sc
		366045 HSP82_YEAST (1-709): 0: 984: 100.00		PRS7_YEAST (83-391): 1.16e-104: 318: 51.78
+	Sc
		543845 HSC82_YEAST (1-709): 0: 973: 94.64		PRS4_YEAST (72-395): 3.99e-106: 321: 49.85
+	Sc
		543463 HSC82_YEAST (1-709): 0: 973: 94.64		PRS7_YEAST (83-391): 1.16e-104: 318: 51.78
+	Dm
		1181035 Q9VAY2_DROME (3-680): 0: 837: 46.67		Q7KMQ0_DROME (60-390): 1.44e-108: 327: 51.05