HitPredict

Interactor 1: HSP82 (P02829)
ATP-dependent molecular chaperone HSP82 (82 kDa heat shock protein) (Heat shock protein Hsp90 heat-inducible isoform)
Gene: HSP82

Interactor 2: WDR59 (Q03897)
Maintenance of telomere capping protein 5 (SEH-associated protein 3)
Gene: MTC5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	11805837
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 709 Sc			1 1148
+	Hs
		437971 HS90B_HUMAN (5-709): 0: 1026: 62.13		LIS1_HUMAN (154-488): 3.85e-46: 173: 12.24
+	Hs
		431630 HS90A_HUMAN (4-709): 0: 1015: 60.83		LIS1_HUMAN (154-488): 3.85e-46: 173: 12.24
+	Sc
		366452 HSP82_YEAST (1-709): 0: 984: 100.00		COPB2_YEAST (2-364): 3.6e-36: 150: 11.14
+	Sc
		543926 HSC82_YEAST (1-709): 0: 973: 94.64		COPB2_YEAST (2-364): 3.6e-36: 150: 11.14
+	Hs
		438414 HS90B_HUMAN (5-709): 0: 1026: 62.13		FBXW7_HUMAN (230-532): 4.61e-19: 95: 5.83
+	Hs
		438474 HS90B_HUMAN (5-709): 0: 1026: 62.13		GRWD1_HUMAN (143-329): 3.41e-17: 87.6: 15.18
+	Hs
		432132 HS90A_HUMAN (4-709): 0: 1015: 60.83		FBXW7_HUMAN (230-532): 4.61e-19: 95: 5.83
+	Hs
		432208 HS90A_HUMAN (4-709): 0: 1015: 60.83		GRWD1_HUMAN (143-329): 3.41e-17: 87.6: 15.18
+	Hs
		152851 HS90A_HUMAN (4-709): 0: 1015: 60.83		APAF_HUMAN (372-582): 1.93e-16: 87.2: 6.16
+	Hs
		438057 HS90B_HUMAN (5-709): 0: 1026: 62.13		GBB2_HUMAN (295-492): 6.76e-13: 73.4: 10.00
+	Hs
		438048 HS90B_HUMAN (5-709): 0: 1026: 62.13		WDR5_HUMAN (1-97): 8.99e-10: 63.7: 13.59
+	At
		646598 HS901_ARATH (3-709): 0: 1001: 64.03		HTD1_ARATH (111-341): 4.7e-17: 87.6: 16.14
+	Hs
		538141 ENPL_HUMAN (3-684): 0: 904: 45.97		LIS1_HUMAN (154-488): 3.85e-46: 173: 12.24
+	Sc
		544654 HSC82_YEAST (1-709): 0: 973: 94.64		YP247_YEAST (63-415): 1.28e-15: 83.3: 16.67
+	Ce
		953942 HSP90_CAEEL (3-709): 0: 947: 60.20		LIN53_CAEEL (23-187): 2.27e-24: 109: 16.02
+	Sc
		366847 HSP82_YEAST (1-709): 0: 984: 100.00		RRB1_YEAST (113-232): 8.69e-09: 61.6: 31.01
+	Sc
		544369 HSC82_YEAST (1-709): 0: 973: 94.64		RRB1_YEAST (113-232): 8.69e-09: 61.6: 31.01
+	Ca
		483034 HSP90_CANAL (4-709): 0: 959: 81.75		TUP1_CANAL (1-100): 6.89e-13: 74.6: 13.21
+	Hs
		282812 ENPL_HUMAN (3-684): 0: 904: 45.97		CIAO1_HUMAN (164-399): 2.77e-26: 113: 13.69
+	Hs
		152853 ENPL_HUMAN (3-684): 0: 904: 45.97		APAF_HUMAN (372-582): 1.93e-16: 87.2: 6.16