Interactor 1: PBPA (P02918)
Penicillin-binding protein 1A (PBP-1a) (PBP1a) [Includes: Penicillin-insensitive transglycosylase (EC 2.4.99.28) (Peptidoglycan TGase); Penicillin-sensitive transpeptidase (EC 3.4.16.4) (DD-transpeptidase)]
Gene: mrcA
Interactor 2: MRDA (P0AD65)
Peptidoglycan D,D-transpeptidase MrdA (EC 3.4.16.4) (Penicillin-binding protein 2) (PBP-2)
Gene: MRDA
Species: Escherichia coli K-12
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.61 | 1.00 | 0.786 |
The method score is based on:
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PCB_OB~Transpeptidase, Transgly~Transpeptidase, PBP_dimer~Transpeptidase, Transpeptidase~Transpeptidase |
| Common GO terms | GO:0005886 - plasma membrane GO:0006508 - proteolysis GO:0008360 - regulation of cell shape GO:0008658 - penicillin binding GO:0009002 - serine-type D-Ala-D-Ala carboxypeptidase activity and 3 others more... |
| Homologous interactions | 16 |
Homologous interactions
Color coding for hit scores 
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| + | Ec |   |
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| + | Aa | |
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| + | Ec | |
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| + | Ss | |
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| + | Ec | |
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| + | Sa | |
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| + | Sa | |
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| + | Ss | |
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| + | Ec | |
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| + | Ss | |
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| + | Bs | |
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| + | Ss | |
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| + | Ss | |
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| + | Sa | |
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| + | Sa | |
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| + | Sp |  |
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Last updated: 15 Jul 2024
