HitPredict

Interactor 1: TOLC (P02930)
Outer membrane protein TolC (Multidrug efflux pump subunit TolC) (Outer membrane factor TolC)
Gene: TOLC

Interactor 2: ACRB (P31224)
Multidrug efflux pump subunit AcrB (AcrAB-TolC multidrug efflux pump subunit AcrB) (Acridine resistance protein B)
Gene: ACRB

Species: Escherichia coli K-12

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.55	0.632

Property	Details
Experiments	29176613, 15228545, 15155734
Identification Methods	affinity chromatography technology, cross-linking study, cosedimentation through density gradient
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0015562 - efflux transmembrane transporter activity GO:0016020 - membrane GO:0030288 - outer membrane-bounded periplasmic space GO:0098567 - periplasmic side of plasma membrane GO:0140330 - xenobiotic detoxification by transmembrane export across the cell outer membrane and 1 others more... GO:1990281 - efflux pump complex
Homologous interactions	0