HitPredict

Interactor 1: DNAA (P03004)
Chromosomal replication initiator protein DnaA
Gene: DNAA

Interactor 2: DNAB (P0ACB0)
Replicative DNA helicase (EC 3.6.4.12)
Gene: DNAB

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.893

The method score is based on:

Property Details
Experiments 8106460, 8702501, 9852089, 10972842
Identification Methods biochemical, coimmunoprecipitation, surface plasmon resonance, solid phase assay
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Bac_DnaA~DnaB_C
Common GO terms GO:0003677 - DNA binding
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006260 - DNA replication
GO:0006268 - DNA unwinding involved in DNA replication
and 2 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 467
Ec

1 471
+ Tp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024