HitPredict

Interactor 1: UVRD (P03018)
DNA helicase II (EC 5.6.2.4) (DNA 3'-5' helicase II)
Gene: UVRD

Interactor 2: MUTL (P23367)
DNA mismatch repair protein MutL
Gene: MUTL

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.75 0.60 0.674

The method score is based on:

Property Details
Experiments 9482750, 10984488, 17765269
Identification Methods two hybrid, biochemical, affinity chromatography technology, comigration in non denaturing gel electrophoresis, far western blotting, surface plasmon resonance
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000717 - nucleotide-excision repair, DNA duplex unwinding
GO:0003677 - DNA binding
GO:0005524 - ATP binding
GO:0006298 - mismatch repair
GO:0016887 - ATP hydrolysis activity
and 2 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 720
Ec

1 615
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024