Interactor 1: GCN4 (P03069)
General control transcription factor GCN4 (Amino acid biosynthesis regulatory protein) (General control protein GCN4)
Gene: GCN4

Interactor 2: MED15 (P19659)
Mediator of RNA polymerase II transcription subunit 15 (Autonomous replication regulatory protein 3) (Basal expression activator protein 1) (Defective silencing suppressor protein 4) (Mediator complex subunit 15) (Transcription regulatory protein GAL11) (Ty insertion suppressor protein 13)
Gene: GAL11

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.55 0.719

The method score is based on:

Property Details
Experiments 11073972, 17919657, 29562181, 20308326, 19940160, 21317429, 22195967
Identification Methods affinity chromatography technology, protein complementation assay, pull down, x-ray crystallography
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0045944 - positive regulation of transcription by RNA polymerase II
GO:0060261 - positive regulation of transcription initiation by RNA polymerase II
GO:0061629 - RNA polymerase II-specific DNA-binding transcription factor binding
Homologous interactions 0

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Last updated: 15 Jul 2024