HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: RLA0 (P05388)
Large ribosomal subunit protein uL10 (60S acidic ribosomal protein P0) (60S ribosomal protein L10E)
Gene: RPLP0

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.678

Property	Details
Experiments	20308691, 21182205, 21182203, 25604459
Identification Methods	affinity chromatography technology, cosedimentation through density gradient, pull down, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 595 Hs			1 317
+	Hs
		370051 ESR1_HUMAN (1-595): 0: 599: 100.00		RLA0L_HUMAN (1-317): 6.83e-147: 417: 98.11
+	Hs
		401019 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		RLA0_HUMAN (1-317): 3.27e-151: 428: 100.00
+	Hs
		1246087 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		RLA0L_HUMAN (1-317): 6.83e-147: 417: 98.11
+	Hs
		1269889 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		MRT4_HUMAN (1-198): 5.69e-82: 249: 22.66
+	Hs
		400711 PRGR_HUMAN (183-508): 6.92e-44: 170: 32.14		RLA0_HUMAN (1-317): 3.27e-151: 428: 100.00
+	Hs
		488033 RARA_HUMAN (81-545): 1.35e-102: 320: 22.37		MRT4_HUMAN (1-198): 5.69e-82: 249: 22.66