HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: CSRP1 (P21291)
Cysteine and glycine-rich protein 1 (Cysteine-rich protein 1) (CRP) (CRP1) (Epididymis luminal protein 141) (HEL-141)
Gene: CSRP1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	25640309
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0008270 - zinc ion binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 595 Hs			1 193
+	Hs
		370509 ESR1_HUMAN (1-595): 0: 599: 100.00		PDLI7_HUMAN (68-190): 3.94e-26: 105: 16.54
+	Hs
		370645 ESR1_HUMAN (1-595): 0: 599: 100.00		LIMA1_HUMAN (3-117): 9.06e-21: 91: 27.83
+	Hs
		150502 ESR1_HUMAN (1-595): 0: 599: 100.00		ABLM1_HUMAN (119-192): 6.1e-14: 71.2: 27.03
+	Hs
		369176 ESR1_HUMAN (1-595): 0: 599: 100.00		PAXI_HUMAN (6-67): 2.97e-11: 63.1: 27.42
+	Hs
		597770 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		CSRP1_HUMAN (1-178): 5.58e-43: 144: 100.00
+	Hs
		1269706 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		PDLI7_HUMAN (68-190): 3.94e-26: 105: 16.54
+	Hs
		1269355 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		PDLI5_HUMAN (7-126): 2.88e-24: 100: 17.50
+	Hs
		1269855 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		LIMA1_HUMAN (3-117): 9.06e-21: 91: 27.83
+	Hs
		377355 GCR_HUMAN (5-557): 4.67e-109: 346: 22.51		CSRP2_HUMAN (1-193): 2.04e-46: 152: 79.28
+	Hs
		1186078 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		MICA3_HUMAN (3-118): 4.43e-18: 83.3: 27.94
+	Hs
		1269296 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		LPP_HUMAN (64-186): 5.27e-16: 77.1: 18.52
+	Hs
		150608 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		ABLM1_HUMAN (119-192): 6.1e-14: 71.2: 27.03
+	Hs
		823459 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		PAXI_HUMAN (6-67): 2.97e-11: 63.1: 27.42
+	Hs
		238944 GCR_HUMAN (5-557): 4.67e-109: 346: 22.51		LPXN_HUMAN (4-128): 1.51e-22: 95.1: 15.20
+	Hs
		200153 GCR_HUMAN (5-557): 4.67e-109: 346: 22.51		TGFI1_HUMAN (6-67): 2.14e-10: 60.8: 27.42
+	Hs
		200156 ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16		TGFI1_HUMAN (6-67): 2.14e-10: 60.8: 27.42