HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: GATA3 (P23771)
Trans-acting T-cell-specific transcription factor GATA-3 (GATA-binding factor 3)
Gene: GATA3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 0.60 0.588

The method score is based on:

Property Details
Experiments 23403292, 25303530
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, chromatin immunoprecipitation assay
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001223 - transcription coactivator binding
and 13 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 595
Hs

1 443
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024