Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: CCN2 (P29279)
CCN family member 2 (Cellular communication network factor 2) (Connective tissue growth factor) (Hypertrophic chondrocyte-specific protein 24) (Insulin-like growth factor-binding protein 8) (IBP-8) (IGF-binding protein 8) (IGFBP-8)
Gene: CCN2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 0.60 0.594

The method score is based on:

Property Details
Experiments 21629692
Identification Methods two hybrid, pull down, anti tag coimmunoprecipitation, enzyme linked immunosorbent assay
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005794 - Golgi apparatus
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
GO:0010629 - negative regulation of gene expression
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 595
Hs

1 349
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024