Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1
Interactor 2: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 0.60 | 0.765 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12400015, 11244506, 27977889, 11782371, 29367421, 17392432, 35430604, 16061635, 20060929, 19887647, 15674350, 17505062, 25499220, 31527615, 16860316, unassigned1953 |
| Identification Methods | pull down, affinity chromatography technology, enzymatic study, anti bait coimmunoprecipitation, tandem affinity purification, anti tag coimmunoprecipitation, coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0006357 - regulation of transcription by RNA polymerase II and 5 others more... |
| Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
