HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: RS4X (P62701)
Small ribosomal subunit protein eS4, X isoform (40S ribosomal protein S4) (SCR10) (Single copy abundant mRNA protein)
Gene: RPS4X

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.678

Property	Details
Experiments	20308691, 21182205, 21182203, 25604459
Identification Methods	affinity chromatography technology, cosedimentation through density gradient, pull down, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 595 Hs			1 263
+	Hs
		915029 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		RS4X_HUMAN (1-263): 4.71e-157: 438: 100.00
+	Hs
		603859 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		RS4Y1_HUMAN (1-263): 9.77e-153: 427: 92.78
+	Mm
		509298 RARA_MOUSE (81-545): 8.36e-104: 323: 22.37		RS4X_MOUSE (1-263): 4.71e-157: 438: 100.00
+	Hs
		740494 PPARG_HUMAN (55-546): 2.12e-100: 316: 20.35		RS4X_HUMAN (1-263): 4.71e-157: 438: 100.00
+	Hs
		487301 ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16		RS4X_HUMAN (1-263): 4.71e-157: 438: 100.00
+	Hs
		487131 ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16		RS4Y1_HUMAN (1-263): 9.77e-153: 427: 92.78