HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: GOGA2 (Q08379)
Golgin subfamily A member 2 (130 kDa cis-Golgi matrix protein) (GM130) (GM130 autoantigen) (Golgin-95)
Gene: GOLGA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	21182205
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus GO:0019901 - protein kinase binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 595 Hs			1 1002
+	Hs
		368902 ESR1_HUMAN (1-595): 0: 599: 100.00		MYH6_HUMAN (495-1001): 1.29e-20: 100: 12.23
+	Hs
		370120 ESR1_HUMAN (1-595): 0: 599: 100.00		MY18A_HUMAN (356-887): 3.84e-17: 89.4: 15.82
+	Hs
		995098 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		GOGA2_HUMAN (1-1002): 2.79e-77: 275: 100.00
+	Hs
		369096 ESR1_HUMAN (1-595): 0: 599: 100.00		MYH9_HUMAN (12-375): 3.45e-11: 69.7: 9.87
+	Hs
		659708 RXRB_HUMAN (144-549): 1.9e-111: 345: 27.64		GOGA2_HUMAN (1-1002): 2.79e-77: 275: 100.00
+	Hs
		3225 A0A0S2Z4M5_HUMAN (144-549): 1.49e-108: 337: 27.27		GOGA2_HUMAN (1-1002): 2.79e-77: 275: 100.00
+	Hs
		1270044 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		MYH4_HUMAN (421-973): 1.1e-20: 100: 12.27
+	Hs
		522631 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		MYH7_HUMAN (489-981): 2.76e-18: 93.2: 13.40
+	Hs
		1268061 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		MY18A_HUMAN (356-887): 3.84e-17: 89.4: 15.82
+	Hs
		1269900 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		MYH13_HUMAN (541-1001): 4.4e-15: 82.5: 10.78
+	Hs
		724944 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		MYH9_HUMAN (12-375): 3.45e-11: 69.7: 9.87
+	Hs
		64608 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		MYH7B_HUMAN (333-778): 8.75e-10: 65.1: 13.59
+	Hs
		587127 RXRA_HUMAN (65-551): 4.55e-127: 383: 26.47		MYH9_HUMAN (12-375): 3.45e-11: 69.7: 9.87
+	Hs
		377795 GCR_HUMAN (5-557): 4.67e-109: 346: 22.51		MYH2_HUMAN (513-993): 2.16e-18: 93.2: 12.89
+	Hs
		740537 PPARG_HUMAN (55-546): 2.12e-100: 316: 20.35		GRDN_HUMAN (407-1001): 1.78e-12: 74: 10.63
+	Hs
		487183 ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16		MYH10_HUMAN (449-991): 1.35e-23: 110: 9.74
+	Hs
		487627 ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16		MY18A_HUMAN (356-887): 3.84e-17: 89.4: 15.82