HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: HNRL2 (Q1KMD3)
Heterogeneous nuclear ribonucleoprotein U-like protein 2 (Scaffold-attachment factor A2) (SAF-A2)
Gene: HNRNPUL2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23403292
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 595 Hs			1 747
+	Hs
		370339 ESR1_HUMAN (1-595): 0: 599: 100.00		HNRL1_HUMAN (1-661): 0: 645: 42.07
+	Hs
		369417 ESR1_HUMAN (1-595): 0: 599: 100.00		HNRPU_HUMAN (1-687): 0: 611: 41.71
+	Hs
		1092869 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		HNRL2_HUMAN (1-747): 0: 781: 100.00
+	Mm
		963084 ERR2_MOUSE (92-547): 6.98e-113: 345: 34.42		HNRL2_MOUSE (1-747): 0: 783: 95.05
+	Hs
		611499 NR4A1_HUMAN (64-549): 2.81e-105: 331: 24.54		HNRL1_HUMAN (1-661): 0: 645: 42.07
+	Hs
		377255 GCR_HUMAN (5-557): 4.67e-109: 346: 22.51		HNRPU_HUMAN (1-687): 0: 611: 41.71
+	Mm
		509335 RARA_MOUSE (81-545): 8.36e-104: 323: 22.37		HNRPU_MOUSE (1-687): 0: 610: 43.20
+	Hs
		370257 ESR1_HUMAN (1-595): 0: 599: 100.00		RANB9_HUMAN (199-534): 1.5e-85: 287: 18.91
+	Hs
		370106 ESR1_HUMAN (1-595): 0: 599: 100.00		DDX1_HUMAN (161-539): 6.94e-84: 283: 22.86
+	Hs
		370623 ESR1_HUMAN (1-595): 0: 599: 100.00		ASH2L_HUMAN (119-446): 2.38e-61: 219: 18.53
+	Hs
		377619 GCR_HUMAN (5-557): 4.67e-109: 346: 22.51		RANB9_HUMAN (199-534): 1.5e-85: 287: 18.91
+	Hs
		1055259 HNF4G_HUMAN (174-594): 3.43e-112: 343: 23.28		RANB9_HUMAN (199-534): 1.5e-85: 287: 18.91
+	Hs
		601671 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		RYR1_HUMAN (182-479): 4.83e-59: 220: 16.45
+	Hs
		1269829 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		ASH2L_HUMAN (119-446): 2.38e-61: 219: 18.53
+	Mm
		509337 RARA_MOUSE (81-545): 8.36e-104: 323: 22.37		DDX1_MOUSE (161-539): 5.32e-82: 278: 22.86
+	Hs
		782681 HNF4A_HUMAN (146-592): 2.13e-118: 361: 20.58		ASH2L_HUMAN (119-446): 2.38e-61: 219: 18.53
+	Hs
		377091 GCR_HUMAN (5-557): 4.67e-109: 346: 22.51		RYR1_HUMAN (182-479): 4.83e-59: 220: 16.45
+	Hs
		377771 GCR_HUMAN (5-557): 4.67e-109: 346: 22.51		ASH2L_HUMAN (119-446): 2.38e-61: 219: 18.53
+	Mm
		1142704 ERR2_MOUSE (92-547): 6.98e-113: 345: 34.42		ASH2L_MOUSE (119-446): 4.5e-61: 218: 18.53
+	Hs
		377394 GCR_HUMAN (5-557): 4.67e-109: 346: 22.51		RN123_HUMAN (278-441): 3.42e-39: 158: 24.85