HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: SCYL2 (Q6P3W7)
SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa)
Gene: SCYL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.594

Property	Details
Experiments	33731348, 21182205
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 595 Hs			1 929
+	Hs
		1159508 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		SCYL2_HUMAN (1-929): 0: 699: 99.14
+	Hs
		369662 ESR1_HUMAN (1-595): 0: 599: 100.00		KS6A1_HUMAN (3-717): 3.6e-138: 432: 12.25
+	Hs
		369218 ESR1_HUMAN (1-595): 0: 599: 100.00		KS6A3_HUMAN (3-717): 1.11e-135: 425: 12.27
+	Hs
		1269375 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		SCYL1_HUMAN (32-807): 9.42e-131: 414: 17.22
+	Hs
		160318 ESR1_HUMAN (1-595): 0: 599: 100.00		AURKA_HUMAN (28-326): 7.69e-63: 220: 24.42
+	Hs
		587205 RXRA_HUMAN (65-551): 4.55e-127: 383: 26.47		KS6A6_HUMAN (6-678): 1.34e-126: 402: 12.47
+	Hs
		611521 NR4A1_HUMAN (64-549): 2.81e-105: 331: 24.54		KS6A6_HUMAN (6-678): 1.34e-126: 402: 12.47
+	Hs
		1224258 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		PACE1_HUMAN (26-511): 4.58e-86: 293: 19.25
+	Hs
		487459 ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16		KS6A1_HUMAN (3-717): 3.6e-138: 432: 12.25