HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: LARP1 (Q6PKG0)
La-related protein 1 (La ribonucleoprotein domain family member 1)
Gene: LARP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	33731348, 21182205
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 595 Hs			1 1096
+	Hs
		1162629 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		LARP1_HUMAN (1-1096): 0: 747: 100.00
+	Hs
		487534 ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16		LARP1_HUMAN (1-1096): 0: 747: 100.00
+	Hs
		369735 ESR1_HUMAN (1-595): 0: 599: 100.00		LARP7_HUMAN (399-925): 2.04e-79: 273: 15.37
+	Hs
		368814 ESR1_HUMAN (1-595): 0: 599: 100.00		LA_HUMAN (400-800): 4.26e-76: 258: 17.43
+	Hs
		369877 ESR1_HUMAN (1-595): 0: 599: 100.00		LARP4_HUMAN (309-860): 6.21e-41: 164: 13.73
+	Hs
		370121 ESR1_HUMAN (1-595): 0: 599: 100.00		LAR4B_HUMAN (274-867): 1.43e-32: 138: 13.23
+	Hs
		370263 ESR1_HUMAN (1-595): 0: 599: 100.00		MINT_HUMAN (3-868): 5.17e-30: 131: 12.77
+	Hs
		1116426 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		LARP7_HUMAN (399-925): 2.04e-79: 273: 15.37
+	Hs
		403300 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		LA_HUMAN (400-800): 4.26e-76: 258: 17.43
+	Hs
		377004 GCR_HUMAN (5-557): 4.67e-109: 346: 22.51		LA_HUMAN (400-800): 4.26e-76: 258: 17.43
+	Hs
		403093 RXRB_HUMAN (144-549): 1.9e-111: 345: 27.64		LA_HUMAN (400-800): 4.26e-76: 258: 17.43
+	Hs
		1268129 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		LAR4B_HUMAN (274-867): 1.43e-32: 138: 13.23
+	Hs
		782640 HNF4A_HUMAN (146-592): 2.13e-118: 361: 20.58		MINT_HUMAN (3-868): 5.17e-30: 131: 12.77
+	Hs
		1270066 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		PCLO_HUMAN (9-866): 1.52e-12: 74.5: 9.86
+	Hs
		377624 GCR_HUMAN (5-557): 4.67e-109: 346: 22.51		MINT_HUMAN (3-868): 5.17e-30: 131: 12.77
+	Hs
		403066 ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16		LA_HUMAN (400-800): 4.26e-76: 258: 17.43