HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: LARP4 (Q71RC2)
La-related protein 4 (La ribonucleoprotein domain family member 4)
Gene: LARP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21182205
Identification Methods	affinity chromatography technology
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 595 Hs			1 724
+	Hs
		370121 ESR1_HUMAN (1-595): 0: 599: 100.00		LAR4B_HUMAN (9-724): 5.72e-59: 214: 32.70
+	Hs
		368814 ESR1_HUMAN (1-595): 0: 599: 100.00		LA_HUMAN (119-325): 8.13e-45: 167: 15.66
+	Hs
		369735 ESR1_HUMAN (1-595): 0: 599: 100.00		LARP7_HUMAN (123-365): 8.03e-34: 139: 17.22
+	Hs
		369844 ESR1_HUMAN (1-595): 0: 599: 100.00		LARP1_HUMAN (98-620): 1.39e-30: 131: 14.72
+	Hs
		370105 ESR1_HUMAN (1-595): 0: 599: 100.00		TITIN_HUMAN (369-718): 1.64e-09: 64: 10.26
+	Hs
		1268129 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		LAR4B_HUMAN (9-724): 5.72e-59: 214: 32.70
+	Hs
		403300 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		LA_HUMAN (119-325): 8.13e-45: 167: 15.66
+	Hs
		1116426 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		LARP7_HUMAN (123-365): 8.03e-34: 139: 17.22
+	Hs
		1162629 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		LARP1_HUMAN (98-620): 1.39e-30: 131: 14.72
+	Hs
		377004 GCR_HUMAN (5-557): 4.67e-109: 346: 22.51		LA_HUMAN (119-325): 8.13e-45: 167: 15.66
+	Hs
		403093 RXRB_HUMAN (144-549): 1.9e-111: 345: 27.64		LA_HUMAN (119-325): 8.13e-45: 167: 15.66
+	Hs
		1264774 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		TITIN_HUMAN (369-718): 1.64e-09: 64: 10.26
+	Hs
		377539 GCR_HUMAN (5-557): 4.67e-109: 346: 22.51		TITIN_HUMAN (369-718): 1.64e-09: 64: 10.26
+	Hs
		403066 ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16		LA_HUMAN (119-325): 8.13e-45: 167: 15.66
+	Hs
		487534 ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16		LARP1_HUMAN (98-620): 1.39e-30: 131: 14.72