HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: PSMD1 (Q99460)
26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit p112)
Gene: PSMD1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.585

Property	Details
Experiments	20348541, 25604459
Identification Methods	pull down, tandem affinity purification
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 595 Hs			1 953
+	Hs
		1269435 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		PSMD1_HUMAN (1-953): 0: 1310: 100.00
+	Hs
		740586 PPARG_HUMAN (55-546): 2.12e-100: 316: 20.35		PSMD1_HUMAN (1-953): 0: 1310: 100.00
+	Hs
		487705 ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16		PSMD1_HUMAN (1-953): 0: 1310: 100.00
+	Hs
		369522 ESR1_HUMAN (1-595): 0: 599: 100.00		PSMD2_HUMAN (8-796): 0: 802: 18.73
+	Hs
		1027740 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		PSMD2_HUMAN (8-796): 0: 802: 18.73
+	Hs
		487393 ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16		PSMD2_HUMAN (8-796): 0: 802: 18.73