HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: DNJC7 (Q99615)
DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2)
Gene: DNAJC7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27483141
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 595 Hs			1 494
+	Hs
		174531 ESR1_HUMAN (1-595): 0: 599: 100.00		OGT1_HUMAN (3-401): 1.62e-31: 130: 13.59
+	Hs
		369072 ESR1_HUMAN (1-595): 0: 599: 100.00		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Hs
		370632 ESR1_HUMAN (1-595): 0: 599: 100.00		DNJB4_HUMAN (380-479): 7.53e-18: 86.7: 45.22
+	Hs
		369057 ESR1_HUMAN (1-595): 0: 599: 100.00		CDC27_HUMAN (4-128): 1.63e-15: 81.6: 20.80
+	Hs
		369237 ESR1_HUMAN (1-595): 0: 599: 100.00		PPP5_HUMAN (242-391): 7.28e-09: 60.1: 31.79
+	Hs
		377633 GCR_HUMAN (5-557): 4.67e-109: 346: 22.51		DNJC7_HUMAN (1-494): 2.58e-85: 273: 100.00
+	Hs
		437650 MCR_HUMAN (21-554): 3.98e-103: 335: 22.01		DNJC7_HUMAN (1-494): 2.58e-85: 273: 100.00
+	Hs
		740587 PPARG_HUMAN (55-546): 2.12e-100: 316: 20.35		DNJC7_HUMAN (1-494): 2.58e-85: 273: 100.00
+	Hs
		175077 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		OGT1_HUMAN (3-401): 1.62e-31: 130: 13.59
+	Hs
		1269841 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		DNJB4_HUMAN (380-479): 7.53e-18: 86.7: 45.22
+	Hs
		672868 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		CDC27_HUMAN (4-128): 1.63e-15: 81.6: 20.80
+	Mm
		1142687 ERR2_MOUSE (92-547): 6.98e-113: 345: 34.42		OGT1_MOUSE (3-401): 1.38e-31: 131: 13.59
+	Hs
		858657 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		PPP5_HUMAN (242-391): 7.28e-09: 60.1: 31.79
+	Hs
		377132 GCR_HUMAN (5-557): 4.67e-109: 346: 22.51		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Hs
		377572 GCR_HUMAN (5-557): 4.67e-109: 346: 22.51		TTC28_HUMAN (1-320): 1.04e-19: 95.1: 15.27
+	Hs
		320215 ERR2_HUMAN (92-547): 4.3e-116: 354: 34.86		DNJB8_HUMAN (381-482): 1.21e-15: 78.2: 44.35
+	Mm
		56867 ERR2_MOUSE (92-547): 6.98e-113: 345: 34.42		CDC27_MOUSE (4-128): 1.26e-15: 82: 20.80
+	Hs
		377203 GCR_HUMAN (5-557): 4.67e-109: 346: 22.51		PPP5_HUMAN (242-391): 7.28e-09: 60.1: 31.79
+	Hs
		437629 MCR_HUMAN (21-554): 3.98e-103: 335: 22.01		PPP5_HUMAN (242-391): 7.28e-09: 60.1: 31.79
+	Hs
		414449 PRGR_HUMAN (183-508): 6.92e-44: 170: 32.14		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49