HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: WDR26 (Q9H7D7)
WD repeat-containing protein 26 (CUL4- and DDB1-associated WDR protein 2) (Myocardial ischemic preconditioning up-regulated protein 2)
Gene: WDR26

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	25604459
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 595 Hs			1 661
+	Hs
		1269625 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		WDR26_HUMAN (28-661): 5.33e-158: 471: 100.00
+	Hs
		370309 ESR1_HUMAN (1-595): 0: 599: 100.00		TBL1Y_HUMAN (396-661): 1.24e-60: 213: 19.72
+	Hs
		369669 ESR1_HUMAN (1-595): 0: 599: 100.00		TAF5_HUMAN (450-661): 8.05e-55: 202: 14.58
+	Hs
		369721 ESR1_HUMAN (1-595): 0: 599: 100.00		SMU1_HUMAN (477-661): 1.05e-44: 169: 17.41
+	Hs
		369932 ESR1_HUMAN (1-595): 0: 599: 100.00		WDR5B_HUMAN (179-512): 1.46e-45: 166: 14.29
+	Hs
		369305 ESR1_HUMAN (1-595): 0: 599: 100.00		WDR5_HUMAN (186-512): 3.62e-45: 165: 15.18
+	Hs
		369344 ESR1_HUMAN (1-595): 0: 599: 100.00		GBB2_HUMAN (462-661): 1.61e-37: 144: 12.20
+	Hs
		370713 ESR1_HUMAN (1-595): 0: 599: 100.00		WDR3_HUMAN (538-660): 2.95e-20: 97.9: 17.89
+	Hs
		1269467 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		TBL1Y_HUMAN (396-661): 1.24e-60: 213: 19.72
+	Hs
		1074801 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		TAF5_HUMAN (450-661): 8.05e-55: 202: 14.58
+	Hs
		245574 HNF4A_HUMAN (146-592): 2.13e-118: 361: 20.58		TBL1X_HUMAN (396-661): 8.44e-63: 220: 19.79
+	Hs
		1103005 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		SMU1_HUMAN (477-661): 1.05e-44: 169: 17.41
+	Hs
		903403 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		WDR5_HUMAN (186-512): 3.62e-45: 165: 15.18
+	Hs
		782550 HNF4A_HUMAN (146-592): 2.13e-118: 361: 20.58		TAF5_HUMAN (450-661): 8.05e-55: 202: 14.58
+	Hs
		921671 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		GBB2_HUMAN (462-661): 1.61e-37: 144: 12.20
+	Hs
		1269746 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		NLE1_HUMAN (45-428): 8.11e-31: 128: 15.25
+	Hs
		782513 HNF4A_HUMAN (146-592): 2.13e-118: 361: 20.58		WDR5_HUMAN (186-512): 3.62e-45: 165: 15.18
+	Hs
		1146687 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		A16L1_HUMAN (522-652): 1.81e-24: 110: 18.94
+	Hs
		1269936 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		WDR3_HUMAN (538-660): 2.95e-20: 97.9: 17.89
+	Hs
		320198 ERR2_HUMAN (92-547): 4.3e-116: 354: 34.86		GBB2_HUMAN (462-661): 1.61e-37: 144: 12.20