HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: RRBP1 (Q9P2E9)
Ribosome-binding protein 1 (180 kDa ribosome receptor homolog) (RRp) (ES/130-related protein) (Ribosome receptor protein)
Gene: RRBP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33731348
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 595 Hs			1 1410
+	Hs
		1269812 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		RRBP1_HUMAN (1-1410): 6.46e-122: 416: 100.00
+	Hs
		369923 ESR1_HUMAN (1-595): 0: 599: 100.00		KTN1_HUMAN (773-1408): 5.31e-21: 102: 12.92
+	Hs
		148263 ESR1_HUMAN (1-595): 0: 599: 100.00		CTRO_HUMAN (917-1399): 2.41e-20: 100: 18.80
+	Hs
		368902 ESR1_HUMAN (1-595): 0: 599: 100.00		MYH6_HUMAN (559-1162): 5.36e-18: 92.7: 12.32
+	Hs
		368926 ESR1_HUMAN (1-595): 0: 599: 100.00		DESP_HUMAN (681-1171): 5.53e-18: 92.7: 16.96
+	Hs
		369096 ESR1_HUMAN (1-595): 0: 599: 100.00		MYH9_HUMAN (490-1085): 2.8e-15: 83.9: 11.40
+	Hs
		370722 ESR1_HUMAN (1-595): 0: 599: 100.00		TNR6B_HUMAN (73-635): 2.71e-10: 67.7: 13.40
+	Hs
		369901 ESR1_HUMAN (1-595): 0: 599: 100.00		MYH14_HUMAN (1026-1394): 8.29e-09: 62.7: 16.71
+	Hs
		1270044 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		MYH4_HUMAN (548-1208): 3.68e-21: 103: 13.91
+	Hs
		149132 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		CTRO_HUMAN (917-1399): 2.41e-20: 100: 18.80
+	Hs
		551794 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		DESP_HUMAN (681-1171): 5.53e-18: 92.7: 16.96
+	Hs
		522631 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		MYH7_HUMAN (476-1148): 7.27e-18: 92.3: 12.67
+	Hs
		724944 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		MYH9_HUMAN (490-1085): 2.8e-15: 83.9: 11.40
+	Hs
		1150622 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		MRCKG_HUMAN (489-832): 5.42e-09: 63.1: 15.14
+	Hs
		1189781 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		MYH14_HUMAN (1026-1394): 8.29e-09: 62.7: 16.71
+	Hs
		587127 RXRA_HUMAN (65-551): 4.55e-127: 383: 26.47		MYH9_HUMAN (490-1085): 2.8e-15: 83.9: 11.40
+	Hs
		377444 GCR_HUMAN (5-557): 4.67e-109: 346: 22.51		KTN1_HUMAN (773-1408): 5.31e-21: 102: 12.92
+	Hs
		377068 GCR_HUMAN (5-557): 4.67e-109: 346: 22.51		DESP_HUMAN (681-1171): 5.53e-18: 92.7: 16.96
+	Hs
		551626 PPARG_HUMAN (55-546): 2.12e-100: 316: 20.35		DESP_HUMAN (681-1171): 5.53e-18: 92.7: 16.96
+	Hs
		611526 NR4A1_HUMAN (64-549): 2.81e-105: 331: 24.54		TNR6B_HUMAN (73-635): 2.71e-10: 67.7: 13.40