Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1
Interactor 2: MED23 (Q9ULK4)
Mediator of RNA polymerase II transcription subunit 23 (Activator-recruited cofactor 130 kDa component) (ARC130) (Cofactor required for Sp1 transcriptional activation subunit 3) (CRSP complex subunit 3) (Mediator complex subunit 23) (Protein sur-2 homolog) (hSur-2) (Transcriptional coactivator CRSP130) (Vitamin D3 receptor-interacting protein complex 130 kDa component) (DRIP130)
Gene: MED23
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.72 | 0.60 | 0.660 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 31527615, 11867769, unassigned1953 |
| Identification Methods | affinity chromatography technology, pull down, tandem affinity purification |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005667 - transcription regulator complex GO:0006355 - regulation of DNA-templated transcription GO:0006357 - regulation of transcription by RNA polymerase II and 1 others more... |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
