Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: IRS2 (Q9Y4H2)
Insulin receptor substrate 2 (IRS-2)
Gene: IRS2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 12821935
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
GO:0071889 - 14-3-3 protein binding
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 595
Hs

1 1338
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024