HitPredict

Interactor 1: CFAD (P03953)
Complement factor D (EC 3.4.21.46) (28 kDa adipocyte protein) (Adipsin) (C3 convertase activator) (Properdin factor D)
Gene: Cfd

Interactor 2: FBLN7 (Q501P1)
Fibulin-7 (FIBL-7) (Protein TM14)
Gene: FBLN7

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30550785
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	EGF~Trypsin, FXa_inhibition~Trypsin, Sushi~Trypsin
Common GO terms	GO:0005615 - extracellular space
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 259 Mm			1 440
+	Hs
		409496 HEPS_HUMAN (15-259): 1.34e-98: 295: 30.68		FBLN1_HUMAN (91-342): 1.11e-23: 106: 23.40
+	Hs
		1198216 TM11B_HUMAN (13-253): 7.08e-99: 296: 31.73		AGRE2_HUMAN (190-352): 3.48e-23: 104: 26.29
+	Mm
		94698 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		F2Z4A3_MOUSE (4-95): 2.33e-13: 74.5: 8.70
+	Mm
		372120 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		FBLN3_MOUSE (34-225): 1.7e-13: 74.1: 13.33
+	Mm
		192824 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		NOTC2_MOUSE (5-327): 5.91e-12: 70.3: 12.13
+	Mm
		372692 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		FBLN4_MOUSE (44-205): 2.58e-12: 70.2: 15.57
+	Hs
		1198224 TM11B_HUMAN (13-253): 7.08e-99: 296: 31.73		JAG2_HUMAN (123-330): 4.98e-17: 86: 20.43
+	Hs
		1345092 TMPS4_HUMAN (9-252): 1.75e-97: 293: 35.06		JAG2_HUMAN (123-330): 4.98e-17: 86: 20.43
+	Mm
		372179 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		LTBP1_MOUSE (41-312): 2.5e-09: 61.7: 15.66
+	Mm
		371603 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		FBLN2_MOUSE (168-388): 3e-09: 61.4: 18.97
+	Mm
		372668 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		SLIT2_MOUSE (98-222): 3.12e-09: 61.4: 18.90
+	Mm
		372013 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		SNED1_MOUSE (1-132): 4e-09: 61: 10.61
+	Hs
		589611 KLK2_HUMAN (1-256): 3.23e-97: 287: 32.59		JAG2_HUMAN (123-330): 4.98e-17: 86: 20.43
+	Hs
		1329638 KLK15_HUMAN (16-256): 3.77e-97: 286: 36.61		JAG2_HUMAN (123-330): 4.98e-17: 86: 20.43
+	Hs
		1055016 TMPS4_HUMAN (9-252): 1.75e-97: 293: 35.06		FAT1_HUMAN (4-91): 1.92e-13: 74.9: 9.09
+	Hs
		371464 KLKB1_HUMAN (3-256): 5.99e-100: 306: 30.30		FBN2_HUMAN (133-305): 3.69e-09: 61.2: 31.03
+	Hs
		980428 TM11B_HUMAN (13-253): 7.08e-99: 296: 31.73		NOTC2_HUMAN (5-324): 1.1e-11: 69.5: 11.96
+	Hs
		1053512 TM11B_HUMAN (13-253): 7.08e-99: 296: 31.73		GAS6_HUMAN (205-305): 2.32e-10: 64.7: 37.62
+	Hs
		177760 TMPS2_HUMAN (9-256): 4.56e-97: 294: 29.34		SLIT2_HUMAN (1-133): 2.94e-09: 61.4: 7.25
+	Hs
		296677 TMPS4_HUMAN (9-252): 1.75e-97: 293: 35.06		SLIT2_HUMAN (1-133): 2.94e-09: 61.4: 7.25