HitPredict

Interactor 1: CFAD (P03953)
Complement factor D (EC 3.4.21.46) (28 kDa adipocyte protein) (Adipsin) (C3 convertase activator) (Properdin factor D)
Gene: Cfd

Interactor 2: CD248 (Q91V98)
Endosialin (Tumor endothelial marker 1) (CD antigen CD248)
Gene: CD248

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	30550785
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FXa_inhibition~Trypsin
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 259 Mm			1 765
+	Mm
		371530 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		TRBM_MOUSE (26-414): 9.9e-60: 214: 30.86
+	Mm
		372120 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		FBLN3_MOUSE (109-381): 4.25e-46: 174: 24.10
+	Hs
		270263 KLK2_HUMAN (1-256): 3.23e-97: 287: 32.59		LRP6_HUMAN (232-619): 3.26e-52: 199: 22.25
+	Hs
		270327 KLK15_HUMAN (16-256): 3.77e-97: 286: 36.61		LRP6_HUMAN (232-619): 3.26e-52: 199: 22.25
+	Mm
		372692 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		FBLN4_MOUSE (164-356): 6.13e-26: 113: 24.76
+	Mm
		139744 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		MATN2_MOUSE (277-505): 3.72e-16: 85.1: 13.73
+	Hs
		371465 KLKB1_HUMAN (3-256): 5.99e-100: 306: 30.30		NID2_HUMAN (267-576): 8.65e-19: 93.9: 15.58
+	Hs
		1055016 TMPS4_HUMAN (9-252): 1.75e-97: 293: 35.06		FAT1_HUMAN (9-149): 1.21e-22: 106: 11.41
+	Hs
		409496 HEPS_HUMAN (15-259): 1.34e-98: 295: 30.68		FBLN1_HUMAN (108-362): 2.67e-22: 104: 21.00
+	Hs
		1055020 KLK11_HUMAN (23-256): 1.47e-96: 285: 32.37		FAT1_HUMAN (9-149): 1.21e-22: 106: 11.41
+	Hs
		1053512 TM11B_HUMAN (13-253): 7.08e-99: 296: 31.73		GAS6_HUMAN (273-365): 3.77e-18: 91: 31.00
+	Mm
		94698 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		F2Z4A3_MOUSE (9-96): 9.45e-12: 71.3: 9.28
+	Mm
		372321 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		LRP1_MOUSE (113-337): 3.71e-11: 69.4: 21.83
+	Mm
		371603 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		FBLN2_MOUSE (270-362): 9.13e-09: 61.3: 22.14
+	Hs
		371464 KLKB1_HUMAN (3-256): 5.99e-100: 306: 30.30		FBN2_HUMAN (158-312): 6.77e-09: 61.7: 19.02
+	Hs
		270267 CMA1_HUMAN (18-256): 4.69e-39: 137: 33.74		LRP6_HUMAN (232-619): 3.26e-52: 199: 22.25
+	Hs
		270253 KLK3_HUMAN (25-256): 3.03e-37: 133: 35.37		LRP6_HUMAN (232-619): 3.26e-52: 199: 22.25
+	Hs
		621366 CMA1_HUMAN (18-256): 4.69e-39: 137: 33.74		FAT1_HUMAN (9-149): 1.21e-22: 106: 11.41
+	Hs
		486154 GRAB_HUMAN (24-250): 8.92e-44: 150: 34.48		NOTC1_HUMAN (6-397): 7.19e-09: 61.6: 9.72
+	Hs
		621380 CMA1_HUMAN (18-256): 4.69e-39: 137: 33.74		SORL_HUMAN (4-205): 1.05e-10: 67.8: 5.75