Interactor 1: CARB (P03965)
Carbamoyl phosphate synthase arginine-specific large chain (CPS) (CPSase) (CPSase-arg) (EC 6.3.4.16) (EC 6.3.5.5) (Ammonium-dependent carbamoyl phosphate synthetase) (Arginine-specific carbamoyl phosphate synthetase, ammonia chain) (Carbamoyl phosphate synthase A) (CPS-A) (Glutamine-dependent carbamoyl phosphate synthetase)
Gene: CPA2

Interactor 2: PYR1 (P07259)
Multifunctional protein URA2 (Pyrimidine-specific carbamoyl phosphate synthase-aspartate carbamoyl transferase) (CPSase-ATCase) [Includes: Glutamine-dependent carbamoyl phosphate synthase (EC 6.3.5.5) (Carbamoyl phosphate synthase P) (CPS-P) (CPSase P) (CPSase-ura) (Pyrimidine-specific carbamoyl phosphate synthase); Glutamine amidotransferase (GATase) (GLNase) (EC 3.5.1.2); Ammonium-dependent carbamoyl phosphate synthase (CPS) (CPSase) (EC 6.3.4.16); Aspartate carbamoyltransferase (ATCase) (EC 2.1.3.2) (Aspartate transcarbamylase)]
Gene: URA2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.759

The method score is based on:

Property Details
Experiments 16554755, 16429126
Identification Methods affinity chromatography technology, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CPSase_L_D2~CPSase_L_D2, CPSase_L_D2~CPSase_L_D3, CPSase_L_D2~CPSase_sm_chain, CPSase_L_D2~GATase, CPSase_L_D2~MGS, CPSase_L_D3~CPSase_L_D3, CPSase_L_D3~CPSase_sm_chain, MGS~MGS
Common GO terms GO:0004070 - aspartate carbamoyltransferase activity
GO:0004087 - carbamoyl-phosphate synthase (ammonia) activity
GO:0004088 - carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GO:0004151 - dihydroorotase activity
GO:0005524 - ATP binding
and 7 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1118
Sc

1 2214
+ Hs
+ Dm
+ Sc
+ Sc
+ At
+ Hs
+ Ec
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ec
+ Nv
+ Pf

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Last updated: 15 Jul 2024