Interactor 1: VTNC (P04004)
Vitronectin (VN) (S-protein) (Serum-spreading factor) (V75) [Cleaved into: Vitronectin V65 subunit; Vitronectin V10 subunit; Somatomedin-B]
Gene: VTN

Interactor 2: ITB3 (P05106)
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)
Gene: ITGB3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 1694173
Identification Methods solid phase assay
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005178 - integrin binding
GO:0007155 - cell adhesion
GO:0007160 - cell-matrix adhesion
GO:0014911 - positive regulation of smooth muscle cell migration
GO:0030949 - positive regulation of vascular endothelial growth factor receptor signaling pathway
and 5 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 478
Hs

1 788
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024