HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: RBM25 (P49756)
RNA-binding protein 25 (Arg/Glu/Asp-rich protein of 120 kDa) (RED120) (Protein S164) (RNA-binding motif protein 25) (RNA-binding region-containing protein 7)
Gene: RBM25

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36244648
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005737 - cytoplasm GO:0042981 - regulation of apoptotic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 648 Hs			1 843
+	Mm
		936589 RAF1_MOUSE (1-648): 0: 647: 97.69		ROCK2_MOUSE (192-798): 9.99e-30: 129: 10.88
+	Hs
		374618 RAF1_HUMAN (1-648): 0: 652: 100.00		PHF3_HUMAN (280-432): 6.42e-20: 98.1: 25.33
+	Hs
		373790 RAF1_HUMAN (1-648): 0: 652: 100.00		MYH9_HUMAN (151-803): 4.55e-19: 95.3: 9.50
+	Hs
		373636 RAF1_HUMAN (1-648): 0: 652: 100.00		DESP_HUMAN (125-772): 9.93e-15: 81: 11.43
+	Hs
		373791 RAF1_HUMAN (1-648): 0: 652: 100.00		MYH10_HUMAN (228-817): 4.57e-14: 78.7: 9.49
+	Hs
		488620 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		RBM25_HUMAN (1-843): 8.68e-63: 229: 100.00
+	Hs
		375162 RAF1_HUMAN (1-648): 0: 652: 100.00		MRCKB_HUMAN (297-663): 2e-12: 73.5: 15.33
+	Hs
		374260 RAF1_HUMAN (1-648): 0: 652: 100.00		PLEC_HUMAN (142-787): 2.15e-11: 70.2: 11.30
+	Hs
		542811 BRAF_HUMAN (39-647): 1.29e-170: 507: 55.88		DESP_HUMAN (125-772): 9.93e-15: 81: 11.43
+	Hs
		542888 BRAF_HUMAN (39-647): 1.29e-170: 507: 55.88		GRDN_HUMAN (116-772): 9.29e-12: 71.4: 11.87
+	Hs
		488559 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		DESP_HUMAN (125-772): 9.93e-15: 81: 11.43
+	Dm
		507767 KRAF1_DROME (45-647): 6.35e-165: 491: 44.98		Q9W179_DROME (256-691): 1.38e-16: 87: 12.53
+	Ce
		136795 KRAF1_CAEEL (50-627): 1.76e-151: 459: 35.95		UNC89_CAEEL (163-599): 1.38e-12: 74.2: 12.27
+	Zm
		38829 A0A1D6MPM7_MAIZE (231-642): 5.34e-117: 368: 22.48		A0A1D6NZ16_MAIZE (174-614): 9.2e-13: 74.6: 12.39
+	Hs
		412308 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		LRIQ1_HUMAN (122-709): 5.86e-23: 107: 10.46
+	Hs
		111443 J3QRU1_HUMAN (329-607): 1.4e-105: 332: 33.92		MYH9_HUMAN (151-803): 4.55e-19: 95.3: 9.50
+	Hs
		433272 YES_HUMAN (329-607): 1.22e-105: 332: 33.92		MYH9_HUMAN (151-803): 4.55e-19: 95.3: 9.50
+	Hs
		412058 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		MYH9_HUMAN (151-803): 4.55e-19: 95.3: 9.50
+	Zm
		23570 A0A1D6IA57_MAIZE (308-631): 1.06e-107: 338: 30.06		A0A1D6NZ16_MAIZE (174-614): 9.2e-13: 74.6: 12.39
+	Hs
		411983 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		DESP_HUMAN (125-772): 9.93e-15: 81: 11.43