HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: GBB2 (P62879)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (G protein subunit beta-2) (Transducin beta chain 2)
Gene: GNB2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	7782277, 38496616
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 340
+	Hs
		374390 RAF1_HUMAN (1-648): 0: 652: 100.00		Q6FHM2_HUMAN (1-340): 2.89e-111: 328: 100.00
+	Hs
		374012 RAF1_HUMAN (1-648): 0: 652: 100.00		GBB1_HUMAN (1-340): 1.35e-106: 316: 90.29
+	Hs
		374672 RAF1_HUMAN (1-648): 0: 652: 100.00		SNR40_HUMAN (130-340): 6.93e-58: 192: 23.36
+	Hs
		373991 RAF1_HUMAN (1-648): 0: 652: 100.00		WDR5_HUMAN (263-340): 9.69e-19: 87.4: 26.92
+	Hs
		412122 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		GBB1_HUMAN (1-340): 1.35e-106: 316: 90.29
+	Hs
		412300 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		SNR40_HUMAN (130-340): 6.93e-58: 192: 23.36