HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: FTM (Q68CZ1)
Protein fantom (Nephrocystin-8) (RPGR-interacting protein 1-like protein) (RPGRIP1-like protein)
Gene: RPGRIP1L

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27173435
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C1_1~C2
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 1315
+	Hs
		148266 RAF1_HUMAN (1-648): 0: 652: 100.00		CTRO_HUMAN (1-542): 6.86e-25: 115: 9.73
+	Mm
		936589 RAF1_MOUSE (1-648): 0: 647: 97.69		ROCK2_MOUSE (165-787): 9.88e-24: 111: 10.82
+	Hs
		375074 RAF1_HUMAN (1-648): 0: 652: 100.00		MYH13_HUMAN (201-793): 1.62e-20: 101: 12.50
+	Hs
		373790 RAF1_HUMAN (1-648): 0: 652: 100.00		MYH9_HUMAN (125-627): 6.2e-16: 85.8: 15.48
+	Hs
		373794 RAF1_HUMAN (1-648): 0: 652: 100.00		MYH11_HUMAN (331-785): 6.23e-15: 82.5: 12.72
+	Hs
		373636 RAF1_HUMAN (1-648): 0: 652: 100.00		DESP_HUMAN (57-798): 1.13e-13: 78.7: 10.51
+	Hs
		374373 RAF1_HUMAN (1-648): 0: 652: 100.00		MRCKA_HUMAN (1-372): 2.18e-13: 77.5: 14.21
+	Hs
		375162 RAF1_HUMAN (1-648): 0: 652: 100.00		MRCKB_HUMAN (120-586): 4.94e-12: 73: 14.18
+	Hs
		488765 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		MY18A_HUMAN (1-545): 3.87e-28: 126: 11.03
+	Hs
		542811 BRAF_HUMAN (39-647): 1.29e-170: 507: 55.88		DESP_HUMAN (57-798): 1.13e-13: 78.7: 10.51
+	Hs
		488559 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		DESP_HUMAN (57-798): 1.13e-13: 78.7: 10.51
+	Hs
		412287 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		MY18A_HUMAN (1-545): 3.87e-28: 126: 11.03
+	Hs
		111443 J3QRU1_HUMAN (329-607): 1.4e-105: 332: 33.92		MYH9_HUMAN (125-627): 6.2e-16: 85.8: 15.48
+	Hs
		433272 YES_HUMAN (329-607): 1.22e-105: 332: 33.92		MYH9_HUMAN (125-627): 6.2e-16: 85.8: 15.48
+	Hs
		523231 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		MYH4_HUMAN (260-783): 2.35e-15: 84.1: 11.32
+	Hs
		412058 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		MYH9_HUMAN (125-627): 6.2e-16: 85.8: 15.48
+	Hs
		411983 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		DESP_HUMAN (57-798): 1.13e-13: 78.7: 10.51