HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: REQU (Q92785)
Zinc finger protein ubi-d4 (Apoptosis response zinc finger protein) (BRG1-associated factor 45D) (BAF45D) (D4, zinc and double PHD fingers family 2) (Protein requiem)
Gene: DPF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	37045861
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0006915 - apoptotic process GO:0046872 - metal ion binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 391
+	Hs
		374134 RAF1_HUMAN (1-648): 0: 652: 100.00		CHD3_HUMAN (43-382): 1.44e-49: 181: 13.23
+	Hs
		374244 RAF1_HUMAN (1-648): 0: 652: 100.00		CHD4_HUMAN (32-382): 5.17e-44: 165: 12.73
+	Hs
		374593 RAF1_HUMAN (1-648): 0: 652: 100.00		PHF10_HUMAN (226-384): 1.03e-31: 127: 35.19
+	Hs
		373737 RAF1_HUMAN (1-648): 0: 652: 100.00		KDM5A_HUMAN (309-375): 1.26e-20: 96.4: 35.82
+	Hs
		522990 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		CHD4_HUMAN (32-382): 5.17e-44: 165: 12.73
+	Hs
		412407 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		KMT2B_HUMAN (109-383): 2.28e-41: 157: 19.00
+	Hs
		522925 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		KMT2A_HUMAN (80-388): 8.66e-36: 141: 14.38
+	Hs
		433328 YES_HUMAN (329-607): 1.22e-105: 332: 33.92		KMT2A_HUMAN (80-388): 8.66e-36: 141: 14.38
+	Hs
		412395 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		BAZ2A_HUMAN (329-375): 3.73e-18: 88.7: 51.06