HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: PF21A (Q96BD5)
PHD finger protein 21A (BHC80a) (BRAF35-HDAC complex protein BHC80)
Gene: PHF21A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34709266
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0046872 - metal ion binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 680
+	Hs
		164343 RAF1_HUMAN (1-648): 0: 652: 100.00		TRI66_HUMAN (2-647): 2.96e-69: 248: 14.35
+	Hs
		373737 RAF1_HUMAN (1-648): 0: 652: 100.00		KDM5A_HUMAN (211-656): 1.39e-54: 204: 16.12
+	Hs
		488772 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		PF21A_HUMAN (1-680): 2.54e-112: 355: 100.00
+	Hs
		374244 RAF1_HUMAN (1-648): 0: 652: 100.00		CHD4_HUMAN (324-650): 1.2e-41: 165: 16.04
+	Hs
		374134 RAF1_HUMAN (1-648): 0: 652: 100.00		CHD3_HUMAN (298-617): 4.98e-41: 163: 15.21
+	Hs
		164346 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		TRI66_HUMAN (2-647): 2.96e-69: 248: 14.35
+	Hs
		412395 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		BAZ2A_HUMAN (4-648): 1.81e-50: 192: 11.71
+	Hs
		522990 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		CHD4_HUMAN (324-650): 1.2e-41: 165: 16.04
+	Hs
		217431 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		AIRE_HUMAN (472-538): 1.24e-19: 94.9: 43.06
+	Hs
		217418 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		AIRE_HUMAN (472-538): 1.24e-19: 94.9: 43.06