Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: CRBN (Q96SW2)
Protein cereblon
Gene: CRBN

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 32778845, 36244648
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Yippee-Mis18
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0031333 - negative regulation of protein-containing complex assembly
GO:0046872 - metal ion binding
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 648
Hs

1 442
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024