HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: FYCO1 (Q9BQS8)
FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7)
Gene: FYCO1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	16364241
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus GO:0046872 - metal ion binding
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 1478
+	Hs
		148266 RAF1_HUMAN (1-648): 0: 652: 100.00		CTRO_HUMAN (195-970): 2.82e-38: 159: 15.44
+	Hs
		374257 RAF1_HUMAN (1-648): 0: 652: 100.00		EEA1_HUMAN (1-910): 5.8e-37: 155: 10.89
+	Hs
		373790 RAF1_HUMAN (1-648): 0: 652: 100.00		MYH9_HUMAN (1-843): 7.74e-35: 148: 11.32
+	Hs
		373794 RAF1_HUMAN (1-648): 0: 652: 100.00		MYH11_HUMAN (595-1316): 1.51e-30: 134: 11.96
+	Hs
		373791 RAF1_HUMAN (1-648): 0: 652: 100.00		MYH10_HUMAN (1-594): 9.36e-27: 121: 12.67
+	Hs
		375074 RAF1_HUMAN (1-648): 0: 652: 100.00		MYH13_HUMAN (718-1330): 1.28e-21: 104: 11.35
+	Hs
		373636 RAF1_HUMAN (1-648): 0: 652: 100.00		DESP_HUMAN (232-1121): 6.82e-14: 79.7: 22.05
+	Hs
		374260 RAF1_HUMAN (1-648): 0: 652: 100.00		PLEC_HUMAN (385-1169): 2.58e-09: 64.7: 22.38
+	Hs
		542811 BRAF_HUMAN (39-647): 1.29e-170: 507: 55.88		DESP_HUMAN (232-1121): 6.82e-14: 79.7: 22.05
+	Hs
		488559 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		DESP_HUMAN (232-1121): 6.82e-14: 79.7: 22.05
+	Hs
		111443 J3QRU1_HUMAN (329-607): 1.4e-105: 332: 33.92		MYH9_HUMAN (1-843): 7.74e-35: 148: 11.32
+	Hs
		433272 YES_HUMAN (329-607): 1.22e-105: 332: 33.92		MYH9_HUMAN (1-843): 7.74e-35: 148: 11.32
+	Hs
		412058 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		MYH9_HUMAN (1-843): 7.74e-35: 148: 11.32
+	Hs
		523231 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		MYH4_HUMAN (574-1306): 1.38e-26: 121: 11.92
+	Hs
		411983 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		DESP_HUMAN (232-1121): 6.82e-14: 79.7: 22.05