HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: UN45A (Q9H3U1)
Protein unc-45 homolog A (Unc-45A) (GCUNC-45) (Smooth muscle cell-associated protein 1) (SMAP-1)
Gene: UNC45A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	36244648, 38496616
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005794 - Golgi apparatus GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 944
+	Hs
		374767 RAF1_HUMAN (1-648): 0: 652: 100.00		Q9BPW0_HUMAN (10-180): 2.23e-39: 154: 23.98
+	Hs
		375088 RAF1_HUMAN (1-648): 0: 652: 100.00		CHIP_HUMAN (8-159): 1.54e-35: 139: 29.30
+	Hs
		374290 RAF1_HUMAN (1-648): 0: 652: 100.00		TOM34_HUMAN (2-139): 4.73e-31: 126: 27.54
+	Hs
		374106 RAF1_HUMAN (1-648): 0: 652: 100.00		SPAG1_HUMAN (16-201): 1.08e-25: 116: 22.61
+	Hs
		373773 RAF1_HUMAN (1-648): 0: 652: 100.00		STIP1_HUMAN (4-228): 9.18e-17: 86.8: 15.32
+	Hs
		375059 RAF1_HUMAN (1-648): 0: 652: 100.00		FKBPL_HUMAN (25-135): 1.26e-11: 69.3: 37.93
+	Hs
		1294466 Q96II5_HUMAN (45-646): 9.01e-168: 494: 58.82		Q9BPW0_HUMAN (10-180): 2.23e-39: 154: 23.98
+	Hs
		488828 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		CHIP_HUMAN (8-159): 1.54e-35: 139: 29.30
+	Hs
		542932 BRAF_HUMAN (39-647): 1.29e-170: 507: 55.88		FKBPL_HUMAN (25-135): 1.26e-11: 69.3: 37.93
+	Hs
		523205 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		CHIP_HUMAN (8-159): 1.54e-35: 139: 29.30
+	Mm
		403469 SRC_MOUSE (331-607): 3.87e-105: 330: 33.10		CHIP_MOUSE (17-159): 3.41e-35: 138: 29.05
+	Hs
		412410 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		CHIP_HUMAN (8-159): 1.54e-35: 139: 29.30
+	Hs
		174558 YES_HUMAN (329-607): 1.22e-105: 332: 33.92		OGT1_HUMAN (3-192): 2.53e-24: 112: 12.63
+	Hs
		1167086 KSR2_HUMAN (332-623): 6.72e-43: 168: 34.43		RPAP3_HUMAN (15-343): 5.32e-41: 163: 17.06
+	Hs
		1167083 KSR2_HUMAN (332-623): 6.72e-43: 168: 34.43		Q9BPW0_HUMAN (10-180): 2.23e-39: 154: 23.98
+	Hs
		858637 KSR2_HUMAN (332-623): 6.72e-43: 168: 34.43		PPP5_HUMAN (10-180): 3.77e-39: 154: 23.98
+	Hs
		174981 KSR2_HUMAN (332-623): 6.72e-43: 168: 34.43		OGT1_HUMAN (3-192): 2.53e-24: 112: 12.63