HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: GHC1 (Q9H936)
Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+) symporter 1) (Solute carrier family 25 member 22)
Gene: SLC25A22

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.521

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 323
+	Hs
		542917 BRAF_HUMAN (39-647): 1.29e-170: 507: 55.88		GHC1_HUMAN (1-323): 5.73e-99: 296: 100.00
+	Hs
		488807 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		GHC1_HUMAN (1-323): 5.73e-99: 296: 100.00
+	Hs
		373508 RAF1_HUMAN (1-648): 0: 652: 100.00		ADT2_HUMAN (101-322): 5.12e-38: 138: 18.50
+	Hs
		373923 RAF1_HUMAN (1-648): 0: 652: 100.00		TXTP_HUMAN (5-306): 1.85e-24: 102: 27.10
+	Hs
		375063 RAF1_HUMAN (1-648): 0: 652: 100.00		S2513_HUMAN (229-323): 2.62e-21: 96.5: 32.65
+	Hs
		397239 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		ADT2_HUMAN (101-322): 5.12e-38: 138: 18.50
+	Hs
		488629 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		TXTP_HUMAN (5-306): 1.85e-24: 102: 27.10
+	Hs
		488825 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		S2513_HUMAN (229-323): 2.62e-21: 96.5: 32.65
+	Hs
		488549 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		ADT3_HUMAN (224-322): 3.75e-13: 70.7: 25.49
+	Dm
		507716 KRAF1_DROME (45-647): 6.35e-165: 491: 44.98		ADT_DROME (4-94): 4.19e-09: 58.7: 17.02
+	Hs
		518227 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		ADT3_HUMAN (224-322): 3.75e-13: 70.7: 25.49
+	Dm
		1096612 Q24171_DROME (250-631): 9.45e-49: 185: 36.80		Q7KSQ0_DROME (12-291): 1.04e-32: 125: 31.10