HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: CHD7 (Q9P2D1)
Chromodomain-helicase-DNA-binding protein 7 (CHD-7) (EC 3.6.4.12) (ATP-dependent helicase CHD7)
Gene: CHD7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	36244648, 37045861
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0060324 - face development
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 2997
+	Hs
		229274 RAF1_HUMAN (1-648): 0: 652: 100.00		SMCA5_HUMAN (856-1893): 0: 928: 27.39
+	Hs
		373731 RAF1_HUMAN (1-648): 0: 652: 100.00		SMCA1_HUMAN (812-1864): 0: 922: 26.51
+	Hs
		374134 RAF1_HUMAN (1-648): 0: 652: 100.00		CHD3_HUMAN (549-1971): 0: 836: 26.40
+	Hs
		374244 RAF1_HUMAN (1-648): 0: 652: 100.00		CHD4_HUMAN (607-1892): 0: 820: 26.91
+	Hs
		151471 RAF1_HUMAN (1-648): 0: 652: 100.00		CHD2_HUMAN (538-1907): 0: 814: 26.11
+	Hs
		373905 RAF1_HUMAN (1-648): 0: 652: 100.00		SMCA4_HUMAN (232-1604): 0: 790: 22.42
+	Hs
		229292 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		SMCA5_HUMAN (856-1893): 0: 928: 27.39
+	Hs
		522800 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		SMCA1_HUMAN (812-1864): 0: 922: 26.51
+	Hs
		488761 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		CHD6_HUMAN (2109-2989): 0: 691: 29.39
+	Hs
		522990 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		CHD4_HUMAN (607-1892): 0: 820: 26.91