Interactor 1: PROC (P04070)
Vitamin K-dependent protein C (EC 3.4.21.69) (Anticoagulant protein C) (Autoprothrombin IIA) (Blood coagulation factor XIV) [Cleaved into: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide]
Gene: PROC

Interactor 2: IPSP (P05154)
Plasma serine protease inhibitor (Acrosomal serine protease inhibitor) (Plasminogen activator inhibitor 3) (PAI-3) (PAI3) (Protein C inhibitor) (PCI) (Serpin A5)
Gene: SERPINA5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.755

The method score is based on:

Property Details
Experiments 2551064, 11123896
Identification Methods pull down, biochemical
Interaction Type direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains FXa_inhibition~Serpin, Serpin~Trypsin
Common GO terms GO:0005576 - extracellular region
GO:0005615 - extracellular space
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 461
Hs

1 406
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024