Interactor 1: PDGFA (P04085)
Platelet-derived growth factor subunit A (PDGF subunit A) (PDGF-1) (Platelet-derived growth factor A chain) (Platelet-derived growth factor alpha polypeptide)
Gene: PDGFA
Interactor 2: PGFRB (P09619)
Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)
Gene: PDGFRB
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.44 | 1.00 | 0.665 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 7679113 |
| Identification Methods | competition binding, enzyme linked immunosorbent assay |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PDGF~ig, Ig_3~PDGF |
| Common GO terms | GO:0005161 - platelet-derived growth factor receptor binding GO:0008284 - positive regulation of cell population proliferation GO:0030335 - positive regulation of cell migration GO:0032956 - regulation of actin cytoskeleton organization GO:0035793 - positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway and 5 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
