Interactor 1: LDLR (P01130)
Low-density lipoprotein receptor (LDL receptor)
Gene: LDLR

Interactor 2: APOC3 (P02656)
Apolipoprotein C-III (Apo-CIII) (ApoC-III) (Apolipoprotein C3)
Gene: APOC3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.55 0.458

The method score is based on:

Property Details
Experiments 39499777
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005769 - early endosome
GO:0010989 - negative regulation of low-density lipoprotein particle clearance
GO:0042632 - cholesterol homeostasis
Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 11Aug2025