Interactor 1: TGFB1 (P01137)
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide (LAP); Transforming growth factor beta-1 (TGF-beta-1)]
Gene: TGFB1
Interactor 2: ITB8 (P26012)
Integrin beta-8
Gene: ITGB8
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.691 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 33961781 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Integrin_beta~TGFb_propeptide |
| Common GO terms | GO:0001570 - vasculogenesis GO:0005886 - plasma membrane GO:0007179 - transforming growth factor beta receptor signaling pathway GO:0009986 - cell surface GO:0010628 - positive regulation of gene expression and 2 others more... |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Last updated: 11Aug2025
