HitPredict

Interactor 1: PABP (P04147)
Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (ARS consensus-binding protein ACBP-67) (Polyadenylate tail-binding protein)
Gene: PAB1

Interactor 2: SGN1 (P40561)
RNA-binding protein SGN1
Gene: SGN1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	1.00	0.918

Property	Details
Experiments	11805837, 16429126, 10764794, 15687504, 22836166
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology, two hybrid, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0008143 - poly(A) binding
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 577 Sc			1 250
+	Sc
		376562 PABP_YEAST (1-577): 1.11e-155: 460: 100.00		PABP_YEAST (48-148): 2.54e-19: 88.7: 24.51
+	Sp
		145447 PABP_SCHPO (18-575): 1.62e-134: 408: 49.66		PAB2_SCHPO (1-147): 8.44e-37: 129: 31.76
+	Hs
		474021 PAB4L_HUMAN (216-412): 3.83e-40: 151: 26.26		PABP4_HUMAN (25-152): 1.61e-21: 94.8: 17.05
+	Mm
		665745 TIA1_MOUSE (8-216): 1.06e-40: 153: 21.58		PABP1_MOUSE (25-152): 1.2e-20: 92.5: 18.61
+	At
		1274962 RB45B_ARATH (13-132): 4.63e-17: 85.4: 17.50		PABN1_ARATH (12-198): 5.75e-41: 141: 32.09
+	Hs
		516495 PABP4_HUMAN (3-218): 3.47e-31: 130: 24.79		PABP1_HUMAN (25-152): 1.06e-20: 92.5: 18.61
+	Hs
		516689 PABP3_HUMAN (21-218): 4.94e-30: 126: 25.23		PABP1_HUMAN (25-152): 1.06e-20: 92.5: 18.61
+	Hs
		1199032 PABP5_HUMAN (1-120): 1.45e-16: 83.7: 14.05		PABP2_HUMAN (1-203): 2.78e-34: 126: 25.12
+	Hs
		516576 PABP1_HUMAN (312-407): 8.73e-15: 79.5: 28.87		PABP2_HUMAN (1-203): 2.78e-34: 126: 25.12
+	At
		1340215 RB45B_ARATH (13-132): 4.63e-17: 85.4: 17.50		PABN3_ARATH (2-199): 2.09e-32: 119: 28.79
+	Hs
		516355 NUCL_HUMAN (219-418): 4.27e-23: 105: 20.00		PABP1_HUMAN (25-152): 1.06e-20: 92.5: 18.61
+	Zm
		8143 A0A1D6ELH4_MAIZE (2-225): 6.14e-19: 92.5: 14.29		A0A1D6ELH4_MAIZE (40-152): 2.14e-18: 86: 18.42
+	Hs
		1119141 PABP5_HUMAN (1-120): 1.45e-16: 83.7: 14.05		PAP1L_HUMAN (25-152): 4.71e-21: 93.7: 15.50
+	Hs
		516635 PABP5_HUMAN (1-120): 1.45e-16: 83.7: 14.05		PABP1_HUMAN (25-152): 1.06e-20: 92.5: 18.61
+	Hs
		516339 PABP1_HUMAN (312-407): 8.73e-15: 79.5: 28.87		PABP1_HUMAN (25-152): 1.06e-20: 92.5: 18.61