HitPredict

Interactor 1: PABP (P04147)
Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (ARS consensus-binding protein ACBP-67) (Polyadenylate tail-binding protein)
Gene: PAB1

Interactor 2: SEN1 (Q00416)
Helicase SEN1 (EC 3.6.4.-) (tRNA-splicing endonuclease positive effector)
Gene: SEN1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	16429126, 18342605
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 577 Sc			1 2231
+	Sc
		376676 PABP_YEAST (1-577): 1.11e-155: 460: 100.00		RENT1_YEAST (1067-1998): 4.25e-165: 536: 19.64
+	Hs
		680472 TIA1_HUMAN (8-216): 8.71e-40: 151: 21.58		RENT1_HUMAN (1100-1883): 0: 616: 22.84
+	Hs
		1272294 PABP5_HUMAN (1-120): 1.45e-16: 83.7: 14.05		RENT1_HUMAN (1100-1883): 0: 616: 22.84
+	Hs
		516622 PABP1_HUMAN (312-407): 8.73e-15: 79.5: 28.87		RENT1_HUMAN (1100-1883): 0: 616: 22.84
+	Hs
		230787 PABP5_HUMAN (1-120): 1.45e-16: 83.7: 14.05		AQR_HUMAN (1310-1892): 3.84e-111: 392: 21.13
+	Hs
		1288623 PABP5_HUMAN (1-120): 1.45e-16: 83.7: 14.05		HELZ2_HUMAN (1559-1853): 2.03e-45: 184: 22.01
+	Hs
		1031468 PABP4_HUMAN (3-218): 3.47e-31: 130: 24.79		MOV10_HUMAN (1231-1423): 6.61e-10: 66.7: 21.32
+	Hs
		1288634 PABP5_HUMAN (1-120): 1.45e-16: 83.7: 14.05		MOV10_HUMAN (1231-1423): 6.61e-10: 66.7: 21.32
+	Hs
		516699 PABP1_HUMAN (312-407): 8.73e-15: 79.5: 28.87		MOV10_HUMAN (1231-1423): 6.61e-10: 66.7: 21.32