HitPredict

Interactor 1: PABP (P04147)
Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (ARS consensus-binding protein ACBP-67) (Polyadenylate tail-binding protein)
Gene: PAB1

Interactor 2: NAM8 (Q00539)
Protein NAM8 (Nuclear accommodation of mitochondria protein 8) (U1 snRNP component NAM8)
Gene: NAM8

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	16429126, 21558325
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 577 Sc			1 523
+	Sc
		376562 PABP_YEAST (1-577): 1.11e-155: 460: 100.00		PABP_YEAST (3-323): 4.49e-41: 157: 12.87
+	Hs
		474021 PAB4L_HUMAN (216-412): 3.83e-40: 151: 26.26		PABP4_HUMAN (2-328): 3.82e-46: 172: 11.11
+	Mm
		665745 TIA1_MOUSE (8-216): 1.06e-40: 153: 21.58		PABP1_MOUSE (153-523): 8.37e-36: 143: 13.78
+	Hs
		516495 PABP4_HUMAN (3-218): 3.47e-31: 130: 24.79		PABP1_HUMAN (153-523): 6.99e-36: 143: 13.78
+	Hs
		680422 TIA1_HUMAN (8-216): 8.71e-40: 151: 21.58		TIA1_HUMAN (3-329): 4.37e-29: 120: 13.45
+	Hs
		680439 TIA1_HUMAN (8-216): 8.71e-40: 151: 21.58		TIAR_HUMAN (3-312): 6.51e-29: 119: 14.60
+	Hs
		516689 PABP3_HUMAN (21-218): 4.94e-30: 126: 25.23		PABP1_HUMAN (153-523): 6.99e-36: 143: 13.78
+	Hs
		1119141 PABP5_HUMAN (1-120): 1.45e-16: 83.7: 14.05		PAP1L_HUMAN (3-317): 1.64e-44: 167: 13.00
+	Hs
		516355 NUCL_HUMAN (219-418): 4.27e-23: 105: 20.00		PABP1_HUMAN (153-523): 6.99e-36: 143: 13.78
+	Zm
		8143 A0A1D6ELH4_MAIZE (2-225): 6.14e-19: 92.5: 14.29		A0A1D6ELH4_MAIZE (3-457): 7.87e-36: 143: 11.93
+	Hs
		516635 PABP5_HUMAN (1-120): 1.45e-16: 83.7: 14.05		PABP1_HUMAN (153-523): 6.99e-36: 143: 13.78
+	Hs
		516339 PABP1_HUMAN (312-407): 8.73e-15: 79.5: 28.87		PABP1_HUMAN (153-523): 6.99e-36: 143: 13.78
+	Hs
		474019 PAB4L_HUMAN (216-412): 3.83e-40: 151: 26.26		ELAV2_HUMAN (160-461): 1.51e-12: 70.8: 12.58
+	Hs
		1020249 PABP4_HUMAN (3-218): 3.47e-31: 130: 24.79		ELAV2_HUMAN (160-461): 1.51e-12: 70.8: 12.58
+	Hs
		516471 PABP1_HUMAN (312-407): 8.73e-15: 79.5: 28.87		TIAR_HUMAN (3-312): 6.51e-29: 119: 14.60
+	Hs
		1020306 PABP5_HUMAN (1-120): 1.45e-16: 83.7: 14.05		ELAV2_HUMAN (160-461): 1.51e-12: 70.8: 12.58
+	Hs
		1055876 PABP5_HUMAN (1-120): 1.45e-16: 83.7: 14.05		ELAV3_HUMAN (3-188): 3.58e-12: 70: 12.37
+	Hs
		516484 PABP1_HUMAN (312-407): 8.73e-15: 79.5: 28.87		ELAV2_HUMAN (160-461): 1.51e-12: 70.8: 12.58