HitPredict

Interactor 1: AUTS2 (A0A087WPF7)
Autism susceptibility gene 2 protein homolog
Gene: AUTS2

Interactor 2: EP300 (B2RWS6)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	34637754
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1261 Mm			1 2412
+	Hs
		998923 AUTS2_HUMAN (1-1261): 6.49e-115: 391: 91.85		EP300_HUMAN (1-2412): 0: 1025: 92.76
+	Mm
		70930 Q6PED7_MOUSE (636-1261): 2.91e-58: 215: 100.00		EP300_MOUSE (1-2412): 0: 1076: 100.00
+	Hs
		554303 MUC1_HUMAN (296-1255): 2.4e-51: 200: 8.80		EP300_HUMAN (1-2412): 0: 1025: 92.76
+	Hs
		998984 ASPP1_HUMAN (108-629): 4.32e-27: 121: 11.32		EP300_HUMAN (1-2412): 0: 1025: 92.76
+	Hs
		998713 NCOA6_HUMAN (32-1249): 3.62e-13: 76.6: 8.89		EP300_HUMAN (1-2412): 0: 1025: 92.76
+	Hs
		631529 AUTS2_HUMAN (1-1261): 6.49e-115: 391: 91.85		BRD2_HUMAN (993-1158): 7.65e-38: 156: 29.24
+	Hs
		631600 FBSL_HUMAN (79-930): 8.6e-41: 166: 26.93		BRD2_HUMAN (993-1158): 7.65e-38: 156: 29.24
+	Hs
		554259 MUC1_HUMAN (296-1255): 2.4e-51: 200: 8.80		MUC1_HUMAN (1889-2409): 4.36e-19: 97.2: 10.71
+	Hs
		1300957 CIC_HUMAN (3-1244): 3.82e-10: 67: 9.22		BAZ1A_HUMAN (888-1175): 7.33e-55: 214: 21.71
+	Mm
		1351630 PCLO_MOUSE (309-1256): 2.65e-36: 152: 9.75		PCLO_MOUSE (1792-2394): 2.33e-13: 78.7: 9.15
+	Dm
		532749 Q9VLS7_DROME (32-764): 9.77e-11: 68.9: 9.29		FSH_DROME (1018-1158): 1.45e-35: 151: 28.87
+	Hs
		1199209 CHD7_HUMAN (426-940): 2.55e-18: 93.8: 11.51		PB1_HUMAN (1071-1366): 1.39e-15: 86: 13.98
+	Hs
		1296839 EP400_HUMAN (239-530): 1.1e-10: 68.5: 17.12		BRD8_HUMAN (941-1153): 1.53e-16: 88.7: 18.31
+	Dm
		113976 M9PB30_DROME (40-532): 3.87e-14: 80.1: 10.45		M9PB30_DROME (1771-2096): 5.22e-11: 71: 12.88
+	Hs
		1057773 NCOA6_HUMAN (32-1249): 3.62e-13: 76.6: 8.89		KMT2C_HUMAN (1895-2407): 1.06e-11: 73.2: 13.94
+	Mm
		1207212 NCOA6_MOUSE (9-1260): 1.83e-13: 77.8: 8.83		KMT2C_MOUSE (1940-2411): 3.42e-10: 68.3: 11.61
+	Hs
		1057781 NCOA6_HUMAN (32-1249): 3.62e-13: 76.6: 8.89		CBP_HUMAN (1752-2406): 6.89e-10: 67.1: 12.48
+	Hs
		152667 KMT2D_HUMAN (29-1114): 2.06e-10: 67.8: 9.92		KMT2C_HUMAN (1895-2407): 1.06e-11: 73.2: 13.94
+	Hs
		152675 KMT2D_HUMAN (29-1114): 2.06e-10: 67.8: 9.92		CBP_HUMAN (1752-2406): 6.89e-10: 67.1: 12.48
+	Hs
		1300971 CIC_HUMAN (3-1244): 3.82e-10: 67: 9.22		CHD7_HUMAN (16-417): 1.67e-09: 66: 10.51