Interactor 1: GCR (P04150)
Glucocorticoid receptor (GR) (Nuclear receptor subfamily 3 group C member 1)
Gene: NR3C1

Interactor 2: MCR (P08235)
Mineralocorticoid receptor (MR) (Nuclear receptor subfamily 3 group C member 2)
Gene: NR3C2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.61 1.00 0.783

The method score is based on:

Property Details
Experiments 16131566, 11154266
Identification Methods affinity chromatography technology, pull down, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Hormone_recep~Hormone_recep, Hormone_recep~zf-C4, zf-C4~zf-C4
Common GO terms GO:0000785 - chromatin
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
GO:0004879 - nuclear receptor activity
GO:0005496 - steroid binding
and 9 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 777
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024