HitPredict

Interactor 1: GCR (P04150)
Glucocorticoid receptor (GR) (Nuclear receptor subfamily 3 group C member 1)
Gene: NR3C1

Interactor 2: THIO (P10599)
Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl protein) (SASP) (allergen Hom s Trx)
Gene: TXN

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.614

Property	Details
Experiments	9915858, 19570036
Identification Methods	pull down, two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm and 1 others more... GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 777 Hs			1 105
+	Hs
		377636 GCR_HUMAN (1-777): 0: 933: 100.00		THIOM_HUMAN (5-105): 2.33e-34: 117: 35.92
+	Hs
		377498 GCR_HUMAN (1-777): 0: 933: 100.00		TXND5_HUMAN (12-105): 2.13e-27: 105: 27.00
+	Hs
		368870 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		THIO_HUMAN (1-105): 6.33e-41: 132: 100.00
+	Hs
		368827 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		PDIA1_HUMAN (2-103): 7.44e-23: 92.9: 22.22
+	Hs
		495581 ESR2_HUMAN (286-769): 2.89e-107: 339: 21.34		THIO_HUMAN (1-105): 6.33e-41: 132: 100.00
+	Hs
		202583 ANDR_HUMAN (357-777): 2.54e-100: 332: 45.15		TXNL1_HUMAN (2-105): 1.99e-36: 126: 40.39
+	Hs
		487594 ANDR_HUMAN (357-777): 2.54e-100: 332: 45.15		TXND5_HUMAN (12-105): 2.13e-27: 105: 27.00
+	Hs
		423315 ESR2_HUMAN (286-769): 2.89e-107: 339: 21.34		PDIA1_HUMAN (2-103): 7.44e-23: 92.9: 22.22
+	Hs
		423142 NR4A1_HUMAN (268-762): 5.59e-103: 331: 20.88		PDIA1_HUMAN (2-103): 7.44e-23: 92.9: 22.22